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Vascular Dementia - Binswanger's Disease

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Vascular Dementia

NIH - Medical Encyclopedia Multi-infarct dementia

"Multi-infarct dementia (MID) is the most common form of vascular dementia, which is a deterioration in mental function caused by strokes. 'Multi-infarct' means that multiple areas in the brain have been injured due to a lack of blood. It is estimated that 10 - 20% of all dementias are caused by strokes, making MID the third most common cause of dementia in the elderly, behind Alzheimer's disease and DLBD (dementia of Lewy bodies). MID affects men more often than women. The disorder usually affects people over 55, with the average onset at age 65. Memory loss is often an early symptom of the disorder, followed by trouble making judgments. This often progresses to delirium, hallucinations, and thinking problems. MID may be misdiagnosed as Alzheimer's, or may be found in addition to Alzheimer's disease. The disorder is diagnosed based on history, symptoms, signs, and tests, and by ruling out other causes of dementia, including dementia due to metabolic causes. History may include a past stroke or hypertension. History of the dementia often shows stepwise progression of the condition -- periods of abrupt decline alternating with stable periods of minimal decline. Other characteristics that suggest multi-infarct dementia rather than Alzheimer's disease include: abrupt onset, physical complaints, emotional changes, and localized neurologic signs "

Highlighted Article

Risk factors for vascular dementia in elderly psychiatric outpatients with preserved cognitive functions. (J Neurol Sci. 2007)

"The clinical conditions related to risk factors for VaD were hypertension (48.7%), heart disease (30.8%), hypercholesterolemia (25.6%), diabetes mellitus (23.1%), stroke (12.8%), tryglyceride (12.8%), and obesity (5.1%). In terms of lifestyle, smoking (19.2%), alcohol abuse (16.7%), and sedentarism (14.1%) were other risk factors found. Definite risk factors for VaD were found in 83.3% of the patients."

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