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Cervical Cancer

:: September 2014

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Clinical Guidelines

AHRQ - Initial management of abnormal cervical cytology (Pap smear) and human papillomavirus (HPV) testing: percentage of adult women diagnosed with initial abnormal cervical cytology of atypical squamous cells of undetermined significance (ASCUS) with high-risk HPV type who have follow-up colposcopy within six months of abnormality identified. (2006)

American Cancer Society Guideline for Human Papillomavirus (HPV) Vaccine Use to Prevent Cervical Cancer and Its Precursors (CA Cancer J Clin 2007)

Guidelines Issued for HPV Use to Prevent Cervical Cancer

NCCN Clinical Practice Guidelines in Oncology: Cervical Cancer Screening (2008)

NGC - American Cancer Society guideline for the early detection of cervical neoplasia and cancer. (2002)

NGC - Cervical cancer. (2003)

NGC - Cervical cancer screening. (2005)

NGC - Cervical cancer screening guideline: December 2006. (2006)

NGC - Cervical cancer: screening recommendations, with algorithms, for managing women with abnormal Pap test results. (2004)

NGC - Cervical screening. (2005)


NGC - Human papillomavirus infection. Sexually transmitted diseases treatment guidelines 2002. (2002)

NGC - Management of initial abnormal Pap smear. (2005)

NGC - Primary treatment for locally advanced cervical cancer: concurrent platinum-based chemotherapy and radiation. (2004)

NGC - Role of imaging in cancer of the cervix. (2005)


NGC - Screening for cervical cancer: recommendations and rationale. (2003)

NGC - Self-collected samples for testing of oncogenic human papillomavirus: a clinical practice guideline. (2006)

Ontario Cervical Screening Evidence-Based Guidelines (2005) Full Report (2005)

Quadrivalent Human Papillomavirus Vaccine: Recommendations of the Advisory Committee on Immunization Practices (ACIP) (MMWR 2007)

Internet Sites

Related InfoMedSearch Topics

Related Topics - Highlighted Articles

Sexually Transmitted Diseases (STDs)

CDC - HPV Infection "Genital HPV infection is a sexually transmitted disease (STD) that is caused by human papillomavirus (HPV). Human papillomavirus is the name of a group of viruses that includes more than 100 different strains or types. More than 30 of these viruses are sexually transmitted, and they can infect the genital area of men and women including the skin of the penis, vulva (area outside the vagina), or anus, and the linings of the vagina, cervix, or rectum. ? Some of these viruses are called ?high-risk? types, and may cause abnormal Pap tests. They may also lead to cancer of the cervix, vulva, vagina, anus, or penis. Others are called ?low-risk? types, and they may cause mild Pap test abnormalities or genital warts. Genital warts are single or multiple growths or bumps that appear in the genital area, and sometimes are cauliflower shaped."

Sexually Transmitted Diseases (STDs)

Association of Chlamydia trachomatis with Persistence of High-Risk Types of Human Papillomavirus in a Cohort of Female Adolescents. (Am J Epidemiol. 2005) "Human papillomavirus (HPV) infection is a necessary but not sufficient cause of cervical cancer. While chlamydia infection has been associated with cervical cancer, the meaning of this association remains unclear. The authors' objective was to investigate this association by evaluating whether concurrent genital tract infections are associated with HPV persistence, a precursor to cervical cancer. ? Concurrent infection with C. trachomatis was independently associated with persistence of high-risk HPV types ... Infection with more than one HPV type at the initial visit was also associated with high-risk persistence ... The association between chlamydia infection and cervical cancer may be due to an effect of chlamydia infection on persistence of high-risk HPV."


Diagnosis, Imaging, and Screening


General Information


Risk Factors


Risk Reduction


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